Pregnenolone may be called known as the mother hormone.  All other steroids including testosterone and estrogen are derived from this hormone called Pregenolone. It is very important to maintain optimal pregnenolone levels in the blood, which are critical for a healthy hormone balance. Pregnenolone is also important for proper brain development, cognition, memory, and mood. These dramatic effects on the brain are why pregnenolone is known as a neuro-active steroid. According to studies by the age of 75 our bodies produce 60% less pregnenolone than the levels produced in our mid-thirties. For this reason pregnenolone is one of the biomarkers of aging. Like counting the rings of a tree, by measuring the level of pregnenolone at any given point of a person’s life, it is often possible to make an educated guess as to his or her age.



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  • Fasting Required: NO
  • Preferred Specimen: Serum
  • Reference Range(s):
    Males (18-58 Years) 13-208 ng/dL
    Premenopausal Females (18-51 Years) 7-188 ng/dL
    Postmenopausal Females (59-81 Years) 13-111 ng/dL
    1 Day-59 Days 12-1331 ng/dL
    60 Days-1 Year ≤170 ng/dL
    2-6 Years ≤107 ng/dL
    7-9 Years ≤114 ng/dL
    10-12 Years ≤163 ng/dL
    13-17 Years ≤325 ng/dL
  • Turnaround Time: 5 Days
  • Test Code: 31493